Greeting address: Acad. Sh.A. Ayupov, President of the Academy of Sciences of the Republic of Uzbekistan. Welcome speech of Chairmen: Acad. Sh. Sh. Sagdullaev. Representatives of Relevant Ministries and Government Agencies, Research Institutes of the Academy of Sciences of the Republic of Uzbekistan, and Higher Education Institutions.

Chairmen: Prof. Sh. S. Azimova Secretary: Dr. M.A. Mamatkhanova

Diterpenoid alkaloids: from chemical and technological research to pharmacological studies and pharmaceutical development. S.Y. Yunusov Institute of the Chemistry of Plant Substances, Uzbekistan. Academician.

Integrated system accelerates academic drug research and technology transferring. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China. Professor.

Novel 𝛾-carbolines and carbazoles derivatives. As a promising drug chemotypes for the neurodegenerative disease treatment. Institute of Physiologically Active Compounds, Federal Center “Problems of Chemical Physics and Medicinal Chemistry RAS”, Russia. Academician.

Experience in combating cardiovascular diseases: achievements of Uzbekistan. Republican Specialized Scientific and Practical Medical Center of Cardiology, Uzbekistan. Professor.

Chairmen: Prof. F.M. Tursunkhodjaeva Secretary: PhD. R.F. Mukhamatkhanova

Carvacrol and its biological activities: An updated review. Near East University, Director of The Institute of Graduate Studies, Nicosia-Turkish Republic of North Cyprus. Professor

Therapeutic perspectives in chronic viral infections. Research Institute of Virology, Republican Specialized Scientific and Practical Medical Center of Epidemiology, Microbiology, Infectious and Parasitic Diseases, Uzbekistan. Academician

New compounds based on natural sesquiterpene lactones. Structure and biological activity. JSC “Research and Production Center “Phytochemistry”, Karaganda, Republic of Kazakhstan. Professor

Fluorine-containing pyrroles: from new reactions to practical applications. Lomonosov Moscow State University, Russia. Academician

Terrestrial and marine-derived fungi as sources of interesting molecules for drug discovery. School of Medicine and Biomedical Sciences Abel Salazar (ICBAS) and CIIMAR, Rua de Jorge Viterbo Ferreira, Portugal. Professor

From Allapinin to Aksaritmin: a new generation of domestic antiarrhythmic therapy. Republican Specialized Scientific and Practical Medical Center of Cardiology, Uzbekistan. Professor

Phytochemical investigation and commercialization of health-improving products from medicinal and edible plant resources of Kazakhstan. Research Center for Medicinal Plants, Al-Farabi Kazakh National University, Kazakhstan. Professor

Chairmen: Prof. F.M. Tursunkhodjaeva Secretary: PhD. R.F. Mukhamatkhanova

Making natural products using wood, light, and electricity. Department of Chemistry, Johannes Gutenberg University Mainz, Germany. Professor

Insights into regulatory mechanisms and activation strategies of silent gene clusters in fungi. State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, China. Professor

The plant lignan sevanol and its analogues, a decade of global research aimed at practical application. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Russia. Professor.

Alkaloid profiling of Thalictrum minus L. roots and in vivo assessment of toxicological, biochemical, hematological, and ultrastructural effects following subacute exposure. Department of Pharmaceutical Toxicology and Chemistry, Faculty of Pharmacy, Azerbaijan Medical University, Azerbaijan. Professor.

Molecular dialogues bridging oncology and environment: the transdisciplinary roles of AHR and AChE. State Key Laboratory of Environmental Chemistry and Toxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, China. Professor

Engineering oilseed crops for sustainable production of functional fatty acids. Department of Bioindustry and Bioresource Engineering, Sejong University, Seoul, Republic of Korea. Professor

Chairmen: Prof. Janar Jenis Secretary: Prof. N.Z. Mamadaliyeva.

Asymmetric hydrogenation of ketones and synthesis of chiral drugs. Institute of Elemento-organic Chemistry, Nankai University, China. Academician.

Targeted chemical transformations of natural compounds to obtain promising drug candidates. Institute of Chemistry, Komi Science Centre of the Ural Branch of the Russian Academy of Sciences, Russia. Academician

Targeted anticancer technologies. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Russia. Academician

Broad-spectrum antiviral activity of plant polyphenols against human herpesviruses. A.S. Sadykov Institute of Bioorganic Chemistry of the Academy of Sciences of the Republic of Uzbekistan, Uzbekistan. Academician

Long-term pharmacological treatment of arrhythmias in Russian guidelines: clinical experience with allapinin. Deputy General Director JSC Pharmcenter VILAR, Russia

Stroke in Uzbekistan as a «socially dangerous disease». Tashkent State Medical University, Uzbekistan. Professor

Plant metabolites in drug development. Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, Russia. Professor

Natural products as sources of anti-inflammatory agents: insights from nitric oxide inhibition in LPS-stimulated RAW 264.7 macrophages. Faculty of Pharmacy, Mahasarakham University, Mahasarakham, Thailand. Associate Professor

Natural product discovery from the malayan flora: oils and secondary metabolites Recent insights into essential oils and secondary metabolites. Department of Chemistry, Faculty of Science and Mathematics, Sultan Idris Education University, Malaysia. Associate Professor

Chemo-enzymatic synthesis of nucleoside analogs: Thermodynamic reaction control vs kinetics. Technische Universität Berlin, Chair of Bioprocess Engineering, Germany. Associate Professor

Why are the non-specific reactions catalyzed by E. coli purine nucleoside phosphorylase not explained by classical catalysis mechanisms? Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Russia. Professor

1. A.A. Azamatov — Antidotal Potential of 1,2,3,4-Tetrahydroisoquinoline Derivatives in Acute Alcohol Intoxication: Role of GABAergic Mechanisms. 2. M.A. Agzamova — Evaluation of the Pharmacological Activity of a Composition Containing Metabolites of Leonurus turkestanicus, Astragalus pterocephalus. 3. E.A. Zorina — Enzymatic synthesis and biological evaluation of new 3-deoxyribonucleoside analogues of ribavirin. 4. E.A. Zorina — Structural modification of 2-chlorocordycepin via N⁶-amino acid substitution. 5. A. Mironov — Nucleoside analogues with indazole containing heterocyclic bases. 6. K.F. Uranskaya — Enzymatic synthesis of novel 1,2,4-triazole-3-carboxamide nucleosides: study of substrate specificity of E. coli nucleoside phosphorylases. 7. N.B. Akhmedova — Synthesis and Growth-Inhibitory Activity of Novel Pyrazolo[3,4-d]pyrimidine–Alkaloid Hybrids. 8. K.F. Kuchimov — Anti-Alcohol Potential of 1-Aryl-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinoline Derivatives: In Silico Modeling of Interaction with ADH Orthosteric Sites. 9. G.I. Khamraeva — Synthesis of New Azomethines Based on 3,5-Dialkyl-3,4-Dihydrothieno[2,3-d]pyrimidine-6-carbohydrazide. 10. K.F. Kuchimov — Mannich Aminomethylation of Quercetin with Cytisine and Anabasine. 11. G.N. Kudratov — Synthesis and Structural Characterization of Unsymmetrical Aryl-Heteryl Urea Hybrids. 12. H.N. Olimova — Isolation of Trachelanthamine N-Oxide Alkaloid from Heliotropium lasiocarpum. 13. S.A. Safarova — Synthesis of New Derivatives of Lappaconitine Alkaloid. 14. V.N. Syrov — Ajuga turkestanica is a Promising Source for the Creation of Drugs and Biologically Active Additives of a Metabolic Type of Action. 15. U.M. Omanova — Astragalus leptophysus Plant Is a Source of Cycloartanes. 16. I.E. Yuldashova — Targeted Acylation and Arylsulfonylation of 2-Amino-6-Methoxy-1,3-Benzothiazole. 17. F.A. Zulpanov — Selective Synthesis of Novel S-Alkyl 3-Phenylquinazolin-4(3H)-ones. 18. B.B. Zhuraev — Synthesis of Urea-Bridged Aryl-Heteryl Hybrid Molecules. 19. Sh.Kh. Ibotov — Lipids of Alhagi kirghisorum Schrenk Seeds. 20. D.R. Siddikov — Phenolic Compounds of the Aerial Parts of Cyperus longus. 21. A.A. Ziyaev — Synthesis and Antimicrobial Activity of S-Acyl and S/N-Bisacyl Derivatives of 5-Aryl-2,4-dihydro-1,2,4-triazole-3-thiones. 22. Kh.Sh. Nabiyeva — Synthesis of Bendamustine Analogues Based on 5-Amino-2-Propionylaminobenzimidazole. 23. A. Abdurashidov — Antimicrobial Activity of the Endophytic Fungus Coriolopsis sp. from Aconitum seravschanicum. 24. A. Abdurashidov — Cytotoxic Activities of the Secondary Metabolites of Endophytic Fungus Coriolopsis sp. Isolated from Aconitum seravschanicum. 25. Sh.N. Ismailova — Acute Oral Toxicity Evaluation of the M-15 Compound Isolated from Centaurea belangeriana and a Flavonoid Compound from Centaurea depressa in Mice. 26. T.T. Toshmurodov — Synthesis and Insecticidal Activity of 1-(5-(Benzylthio)-1,3,4-thiadiazol-2-yl)-3-(alkyl, aryl)thioureas. 27. O.B. Alimukhamedova — Identification of Conserved Genomic Regions for Diagnostic Assays in Local Hepatitis B Virus Isolates. 28. Sh.Kh. Rakhimova — Green Extraction and Comparative Characterization of Collagen from Different Tissues of Esox lucius. 29. Sh.Kh. Rakhimova — Development and Preclinical Evaluation of a Plant-Derived Enzymatic Preparation for Targeted Modification of Atherosclerotic Plaques. 30. Sh.Kh. Rakhimova — Complex Post-COVID Gynecological Rehabilitation Using Kukumazim: Clinical Evaluation and Implementation of a Standardized Rehabilitation Program. 31. Sh.Kh. Rakhimova — Proteolytic Therapy of Localized Scleroderma Using Plant-Derived Cysteine Proteases. 32. Sh.Kh. Rakhimova — Isolation, Amino Acid Composition, and Hypoglycemic Activity of Protein Components from Arundo donax L. 33. Sh.Kh. Rakhimova — Protein Fractions of Capparis spinosa L. Buds: Amino Acid Composition, Structural Characterization, and Hypoglycemic and Hypolipidemic Activity. 34. B.F. Jumanov — Synthesis and Study of the Structure of 5-Amino-1,3,4-Thiadiazole-2-Thiol Derivatives. 35. Kh.R. Shamuratova — Quantitative Determination of Polysaccharides and Phenolic Compounds in the “Triburenal” Substance Derived from Tribulus terrestris. 36. T.Z. Khomidov — Visible Mortality, Invisible Disability: A Pilot DALY-Based Assessment of the Stroke Burden in Uzbekistan. 37. T.Z. Khomidov — Integrating the DALY Metric into Health Statistics and Priority-Setting in Uzbekistan: A Four-Stage Roadmap. 38. H.Sh. Kuchkarov — Comparative Antirecurrence Antiarrhythmic Efficacy of Some Fast Sodium Channel Blockers in Patients with Atrial Fibrillation. 39. A.G. Tojiboev — Crystal and Molecular Structures of 1-Alkyl-Quinazolin-4(3H)-ones with p-Chlorophenyl Fragment. 40. F.A. Sadygova — HPLC and Capillary Electrophoresis in the Analysis of the Tefestrol Substance. 41. D.Sh. Aripova — The Influence of Renal Dysfunction Degree on the Development of Endothelial Dysfunction in Patients with Chronic Heart Failure. 42. M.M. Antonova — Low-Molecular-Weight Oleyl Hyaluronan as a Polymeric Carrier in Novel Drug Formulations. 43. P.Zh. Bekisheva — Chromatographic Isolation and Enzyme Inhibition of Lupinine from Anabasis salsa. 44. B. Demirci — Evaluation of Antibacterial Activity of Cupressus sempervirens L. Essential Oil. 45. F. Özdemir — Investigation of the Cytotoxic Effects of Triticum durum Extracts on A549 Cells. 46. A.P. Kalinovskii — Therapeutic Targeting of TRPV3 Channel with Plant Diterpenoid 14-Deoxy-11,12-Didehydroandrographolide. 47. M. Kürkçüoğlu — Essential Oil Composition of Tripleurospermum corymbosum (Asteraceae), an Endangered Stenoendemic Species from Türkiye. 48. K.O. Romashkova — A New Dosage Form of Tefestrol Based on Low-Molecular-Weight Oleyl-Hyaluronan. 49. Y.V. Ulianova — Optimization of Polylactide Microsphere Composition for Controlled Prolonged Release of Betamethasone Acetate. 50. A.Zh. Mendibayeva — Synthesis of Naphthyl- and Alkaloid-Containing Thioureas. 51. D.K. Nurkadirov — Development of a Wound-Healing Ointment Based on Linaria vulgaris Mill. Extract. 52. Zh.S. Nurmaganbetov — Synthesis and Biological Evaluation of Alkaloid Lupinine-Triazole Derivatives as Acetylcholinesterase Inhibitors. 53. Xiao-Hui Ma — Wendan Tablet and Its Active Component Isocurcumenol Protect against Myocardial Ischemia via Targeting ALOX15 and Inhibiting Lipid Peroxidation. 54. A.S. Adekenova — Biologically Active Components of the Essential Oil of Ligularia macrophylla (Ledeb.) DC. 55. A.T. Boldysh — Technology of an Anti-Inflammatory and Wound-Healing Flavonoid Phytofilm. 56. S.N. Mantler — Biosynthesis of Biologically Active Guaianolides. 57. Betül Demirci — Evaluation of Antibacterial Activity Cupressus sempervirens L.Essential Oil Presenting. 58. Р.А. Bukharova — Application of capillary electrophoresis and high-performance liquid chromatography for the quantitative determination of Cynaroside. 59. I.S. Sedalova — Synthesis of N-benzyl derivatives of 1-aryl-1,2,3,4-tetrahydroisoquinolines.

Chairmen: Dr. Sarah Westarp Secretary: Prof. S.A. Sasmakov

Phytochemical characterization and pharmacological properties of some medicinal plants of the Algerian flora. Chemistry Department, Faculty of Matter Sciences, Laboratory of Chemistry and Environmental Chemistry (LCCE), University of Batna, Algeria. Professor.

Modern trends in natural antibiotic discovery. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Russia. PhD

Genetic engineering of Sorangium cellulosum: a platform for decoding myxobacterial secondary metabolism. State Key Laboratory of Microbial Diversity and Innovative Utilization, Institute of Microbiology, Chinese Academy of Sciences, China. Professor

Integrative metabolomics reveals the neuroprotective and antidepressant mechanisms of Oroxylum indicum seed extract in a chronic unpredictable mild stress mouse model. Faculty of Pharmaceutical Sciences, Khon Kaen University, Thailand. Associate Professor

Human cells and their secretome as a tool for regenerative pharmacology. Centre for Regenerative Medicine, Medical Research and Educational Institute, Lomonosov Moscow State University, Russia. Professor

Drug discovery and repositioning studies assisted by artificial intelligence. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China. Professor

Recent phytochemical studies on Astragalus, Polygala, and Teucrium species. Near East University, Faculty of Pharmacy, Department of Pharmacognosy, Lefkoşa, N. Cyprus. Professor

The design and synthesis of the new heterocyclic compound. Department of Chemistry, Middle East Technical University, Türkiye. Professor

Discovery of potent non-opioid analgesics. School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology/ College of Pharmacy, Xinjiang Medical University. Professor

Uvaol ameliorates myocardial infarction by reducing inflammation and pyroptosis via suppression of NLRP3 inflammasome signaling pathway. Institute of Cardiovascular Diseases, School of Medicine, Wuhan University of Science and Technology, China. Associate Professor.

Chemical modifications of plant alkaloids as a reliable strategy for designing and recognizing of new groups of acetylcholinesterase inhibitors. Novosibirsk Institute of Organic Chemistry, SB RAS, Novosibirsk, Russia. Professor

Technology for the development of hydrophobic, biocompatible and selective nanosorbents for medical applications. Central Asian Medical University, Uzbekistan. Professor

Evaluation of the effects of essential oils and hydrosols on the gastrointestinal system. Anadolu University, Faculty of Pharmacy, Department of Pharmacognosy, Eskisehir, Turkiye. Associate Professor

Chairmen: Dr. E.E. Shults Secretary: PhD. B.S. Okhundedaev

Phytochemical study of terpenoids and phenolic compounds of plants of the genus Perovskia of the flora of Uzbekistan. S.Y. Yunusov Institute of the Chemistry of Plant Substances, Uzbekistan. Professor.

Isolation of biologically active compounds from plants of the genera Achillea and Polygonum. JSC «Kazakh University of Business and Information Technologies named after K. Kulazhanov», Kazakhstan. Professor

Phytochemical investigation of selected plant species from the flora of Azerbaijan and their applications. Azerbaijan Medical University, Department of Pharmaceutical Chemistry. Azerbaijan. Professor

Secondary metabolites of genus of Ferula growing in the flora of Uzbekistan and their biological activity. S.Y. Yunusov Institute of the Chemistry of Plant Substances, Uzbekistan. Professor

Terpenoids from Ferula and Phyllanthus spp. and their biological activities. State Key Lab of Phytochemistry & Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, China. Professor

Enzymatic synthesis and antiherpetic activity of alkyl-substituted 5-phenyl-1,2,4-triazole-3-thione deoxyribosides. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Russia. Associate Professor

Natural peptide modulators of TRPA1 and TRPV1 channels increases long-term potentiation in the hippocampus and reduces anxiety and fear in mice. Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Russia. Associate Professor

The cosmeceutical pharmacognosy trends, evidence, and innovation. Department of Pharmacognosy, Faculty of Pharmacy, Lokman Hekim University, Türkiye. Professor

Adaptation potential of endophytic microorganisms in biotechnology and agriculture. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Russia. PhD

Curcumin/chalcone-derived scaffolds as promising bioactive agents: a journey from synthesis to biological evaluation

Cytotoxicity of purine nucleosides with C2 and C6 substituents

Synthesis and antifungal activity of monoterpene alcohols, acids and chlorine-containing derivatives

Synthesis and inhibitory potential of Ugi products towards butyrylcholinesterase

An asymmetric synthesis of finerenone via Evans chiral auxiliary

New antigen-oligonucleotide bioconjugates for multiplex assay of pathogenic bacteria

Functionalized synthetic lipids as molecular tools for cell surface engineering

Application of functionalized synthetic lipids in biology and medicine

New bioactive secondary metabolites from the marine-derived fungi

A new guaianolide sesquiterpene lactone from Ferula kokanica

Preparation and in vitro evaluation of cytotoxic activity of Seseli condensatum l. root extract

Phytochemical investigation of Phlomis bucharica

Chairmen: Prof. F.M. Tursunkhodjaeva Secretary: PhD. F.R. Egamova

Clinical course of COVID-19 in children and evaluation of the efficacy of the domestic drug Rutan in the comprehensive treatment of the disease. Department of Infectious and Pediatric Infectious Diseases, CDPQMW, Uzbekistan. Professor

Combination of photocatalysis and continuous-flow technology for the synthesis of bioactive compounds and its precursors. Department of Organic Chemistry, N.I. Lobachevsky State University of Nizhny Novgorod, Russia. PhD

Courses for advanced training in gynecological cytology, determination of High-risk HPV genotypes in women of reproductive age. Research Institute of Virology, Uzbekistan. PhD

Development of mRNA therapeutics against viral and oncological diseases. Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Russia. PhD

Effects of salicylic acid on photosynthetic pigment content in the leaves of Astragalus sieversianus

Spectrum of HIV-1 drug resistance mutations

Components and action mechanisms of traditional chinese medicine against COVID-19

Clinical masks of Epstein-Barr virus infection and therapeutic aspects

Characteristics of the 2025-2026 acute respiratory infection season in Uzbekistan

Nanomedicine for efficient chemotherapy of brain tumours: from bench to bedside

Design, synthesis, and biological evaluation of novel nucleoside analogues as antiviral agents against dengue

Whole-Genome sequencing identifies a new Aspergillus tubingensis strain from eremostachys isochila with intraspecific variation in pharmaceutically relevant biosynthetic gene clusters

Mitochondria in potential drugs screening – focus on neurodegenerative diseases

Pharmacological study of the vitasteroids sum from Physalis angulata

Molecular targets of CNEURO-201: Evidence from biophysical, cellular, and preclinical animal studies

MicroRNAs in viral infections: biomarkers of disease progression and clinical outcomes

Synthesis and acylation tetrahydroazepino[2,1-b]quinazolin-12(6H)-one

ersistence of High-Risk HPV infection and dynamics of cervical dysplasia in women in the chimbay district during two-stage cervical cancer screening

Artificial intelligence as a tool for supporting clinical decision-making in infectious diseases

Morphofunctional characteristics of the thymus in metabolic syndrome

Analysis of the lipid profile of Crocus sativus L.stamen

Chairmen: Acad. M.S. Yunusov Secretary: PhD. O.T. Jurayev

Antiarrhythmic agents based on diterpenoid alkaloids. Ufa Institute of Chemistry, Ufa Federal Research Centre of the Russian Academy of Sciences, Russia. Academician

Lappaconitine hydrobromide (Allapinin): clinical and experimental prospects. Republican Cardiology Center, Ufa, Russia. Professor

Lappaconitine modifications by multicomponent reactions for preparation of pharmacologically promising agents. N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, Russia. PhD

Antiglycation and anti-inflammatory potential of Aloe barbadensis and Merendera persica. Department of Life Sciences, University of Mumbai, India. Associate Professor

β-Ecdysterone modulates mammalian cell bioenergetics and attenuates mPTP-associated mitochondrial depolarization. Center for Advanced Technologies, Uzbekistan. PhD

Acute toxicity and antiarrhythmic activity of the alkaloid nitraridine. Tashkent State Medical University, Uzbekistan. Professor

Cardioembolic stroke in Uzbekistan: epidemiology and diagnosis. Tashkent State Medical University, Uzbekistan. PhD

Comparative antirecurrence antiarrhythmic efficacy of some fast sodium channel blockers in patients with atrial fibrillation

Personalized approach to the use of Allapinin in cardiac arrhythmias in emergency cardiology

Dynamics of the adipokine profile against the background of cardiac rehabilitation in patients with CHF, obesity, and metabolic syndrome

Design of functional imidazolium ionic liquids for biomedical and environmental applications

Low-molecular-weight oleyl hyaluronan as a polymeric carrier in novel drug formulations

Comparative antibacterial activity of red and black Antidesma bunius fruit extracts against Escherichia coli

Moderators: Prof. N.F. Salakhutdinov Acad. E.I. Musabaev Prof. F.M. Tursunkhodjaeva