Section 1. XVI Symposium «Current problems of chemistry, biology and technology of natural compounds»

CHEMICAL CONSTITUENTS OF Ferula tadshikorum PIMENOV

F. Zokirov 🎤
State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, and Key Laboratory of Chemistry of Plant Resources in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, China; University of Chinese Academy of Sciences, China
Kh. Kamoldinov
State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, and Key Laboratory of Chemistry of Plant Resources in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, China
I. Asqarov
Andijan State University, Uzbekistan
Jiangyu Zhao
State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, and Key Laboratory of Chemistry of Plant Resources in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, China
Haji Akber Aisa
State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, and Key Laboratory of Chemistry of Plant Resources in Arid Regions, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, China; University of Chinese Academy of Sciences, China
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Abstract

The genus Ferula (Apiaceae) comprises around 180–185 species that occur from Central Asia to Northern Africa. The chemical components of essential oils derived from various Ferula species have been shown to exhibit a wide range of biological activities. Ferula tadshikorum Pimenov is a medicinal plant that is endemic to Uzbekistan. Today, it is mainly cultivated there for export to the rest of the world [2]. In our ongoing study, five compounds were isolated from F. tadshikorum by using silica column (CC) and Flash chromatography, Sephadex LH-20 chromatography, along with preparative-HPLC. Their structures were comprehensively elucidated by HRESI-MS, UV, IR, NMR experiments as umbelliferone (1), 4,7-dimethoxy-5-(propanoyl)benzo[d][1,3]dioxole (2), 3-methoxy-4,5-methylenedioxypropiophenone (3), dibutyl phthalate (4), grilactone (5), respectively. All compounds were isolated from this species for the first time.

References

  1. Maryam Salehi, Mohammad Reza Naghavi, Moslem Bahmankar. (2019). A review of Ferula species: Biochemical characteristics, pharmaceutical and industrial applications, and suggestions for biotechnologists.Industrial Crops and Products.[Crossref]
  2. Azizbek Mahmudov, Komiljon Tojibaev, Ozodbek Abduraimov, Bekzod Mavlanov, Akmal Allamurotov. (2025). The current state of natural resources Ferula tadshikorum Pimenov in Uzbekistan.Plant Science Today.[Crossref]

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Publication Details

Published Date07/10/2026
ConferenceInternational Conference “Biologically active compounds: From chemistry to medicine”
DOI10.5281/zenodo.23061788
Pages249
CC BY 4.0

This article is licensed under a Creative Commons Attribution 4.0 International License.