ALKALOIDS FROM Ziziphus jujuba

Abstract

Ziziphus jujuba Mill is a plant belonging to the Rhamnaceae family, widely cultivated as a medicinal fruit tree in Central Asia, including Uzbekistan. It is mainly cultivated. It is also widespread in the southern borders of Uzbekistan (in the Surkhandarya region) in a wild state. In folk medicine, a decoction of the fruit of Ziziphus jujube is used as an expectorant, diuretic, and blood pressure reducer for sore throats and chest pains, and coughs. A decoction of the leaves is used in scientific medicine as a blood pressure reducer and diuretic [1]. The leaves of the wild variety Ziziphus jujuba Mill were first studied.. Six alkaloids were isolated from the leaves of a wild variety of Ziziphus jujuba collected from the Surkhandarya region: previously discovered coclaurin (1), N-methylcoclaurin (2) [2], yuzirin (3), asimilobine (4), norizoboldine (5) and isoboldine (6), which were identified for the first time in this plant.

References

1. Тойжонов К., Ниғматуллаеи О., Сагдуллаев Ш. // Ўзбекистон доривор ўсимликлари лотинча номларининг этимологик луғати. 2016, Тошкент.
2. Hideaki Otsuka, Yukio Ogihara, Shoji Shibata. (1974). Isolation of coclaurine from Zizyphus jujuba by droplet counter-current chromatography.Phytochemistry.[Crossref]
3. Юнусов С. Ю. Алкалоиды Приложение II. (1984-1988 гг) Тошкент, «Фан» нашриёти, 1989, стр. 40-45.
4. Sory Fofana, R. Ziyaev, Saliou Kaby Diallo, Mohamed Camara, S. F. Aripova. (2013). Alkaloids of Annona senegalensis.Chemistry of Natural Compounds.[Crossref]

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