Section 3. Antiarrhythmic preparations – 40 years of allapinin use

PROGNOSTIC SIGNIFICANCE OF VENTRICULAR ECTOPIC ACTIVITY FOR CARDIOVASCULAR MORTALITY IN PATIENTS WITH ATRIAL FIBRILLATION

N.U. Zakirov 🎤
Republican Specialized Scientific and Practical Medical Center of Cardiology, Tashkent, Uzbekistan
A.A. Tolibov
Republican Specialized Scientific and Practical Medical Center of Cardiology, Tashkent, Uzbekistan
Sh.Sh. Xolmurodov
Republican Specialized Scientific and Practical Medical Center of Cardiology, Tashkent, Uzbekistan
M.S. Mahmudov
Republican Specialized Scientific and Practical Medical Center of Cardiology, Tashkent, Uzbekistan
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Abstract

Atrial fibrillation (AF) and ventricular ectopic activity (VEA) are pathological conditions that frequently coexist and significantly increase the risk of cardiovascular mortality. Early identification of patients with a high risk of cardiovascular (CV) death among this population remains one of the most important challenges in contemporary cardiology. To evaluate the prognostic significance of ventricular ectopic activity in predicting cardiovascular mortality in patients with atrial fibrillation. A total of 196 patients with different forms of atrial fibrillation who attended the outpatient consultative department of the Republican Specialized Scientific and Practical Medical Center of Cardiology were included in the study. Among them, 50% were men, and 18 % had valvular AF. The mean age of the study population was 66.08 ± 10.02 years. At initial assessment, clinical characteristics and medical history were recorded, and treatment was adjusted according to the 2024 ESC guidelines. The primary endpoint was all-cause mortality, including cardiovascular deaths. Follow-up was conducted every 3–6 months by telephone or outpatient visits. In cases of death, information was obtained from relatives, while the cause was determined from medical records and witness reports. Statistical analysis was performed using STATISTICA 13, with p<0.05 considered statistically significant.

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Publication Details

Published Date07/10/2026
ConferenceInternational Conference “Biologically active compounds: From chemistry to medicine”
DOI10.5281/zenodo.23061639
Pages225
CC BY 4.0

This article is licensed under a Creative Commons Attribution 4.0 International License.