ASSOCIATION OF OBSTRUCTIVE SLEEP APNEA SEVERITY WITH NOCTURNAL OXYGENATION AND ANTHROPOMETRIC PARAMETERS IN PATIENTS WITH CORONARY ARTERY DISEASE
Abstract
To determine the frequency and severity of OSA among CAD patients who underwent respiratory monitoring, and to assess the association of the apnea–hypopnea index (AHI) with nocturnal oxygenation, anthropometric and cardiovascular parameters. A cross-sectional exploratory analysis of a retrospective clinical database was conducted from January 2025 to June 2026. Of 67 patients, 45 underwent respiratory monitoring, and 38 with confirmed CAD and available AHI data were included. Events were scored according to American Academy of Sleep Medicine criteria and were predominantly obstructive. Variable-specific complete-case analysis was used, with n reported for each result; estimated echocardiographic values were excluded. Patients were stratified by AHI (<5, n=11; 5–14.9, n=5; 15–29.9, n=13; ≥30 h⁻№, n=9), with the main comparison being AHI <15 (n=16) versus ≥15 (n=22). After the Shapiro–Wilk test, groups were compared using Welch’s t-test or Mann–Whitney U test, and four groups using ANOVA or Kruskal–Wallis; categorical variables were analyzed by Fisher’s exact test. Spearman correlation, Firth logistic regression, and ROC analysis were also performed. No multiple-comparison correction was applied; p<0.05 was considered statistically significant.
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