EVALUATION OF ANTIBACTERIAL ACTIVITY Cupressus sempervirens L. ESSENTIAL OIL
Abstract
In recent years, interest in medicinal plants and their oils is increasing due to the development of resistance in antimicrobial treatments, their side effects, and treatment costs. Essential oils, due to their broad antimicrobial, and anti-inflammatory activities, are widely used in the cosmetic and pharmaceutical industries. The essential oil of Cupressus sempervirens L., was obtained from a commercial source, and the chemical profiles of the essential oils was evaluated by gas chromatography and gas chromatography-mass spectroscopy for its chemistry. The in vitro antibacterial activity of the essential was evaluated against acne pathogens Propionibacterium acnes ATCC 11827, and Staphylococcus aureus ATCC 6538 strains using the microdilution method, where the Minimum inhibition concentration (MIC) was compared to Ciprofloxacin which was used as a positive control. a-Pinene (44.9%), d-3-carene (19.3%), 1,8-cineole (9.2%), and limonene (3.7%) were verified as main components of essential oil. The MIC values of essential oil were calculated as 3.12 and 1.56 mg/mL against P. acnes and S. aureus strains, respectively. Based on these initial results, the essential oil may be an effective agent for the treatment of acne, which has to be verified by more detailed in vivo and clinical studies.
Publication Details
This article is licensed under a Creative Commons Attribution 4.0 International License.