BIOLOGICALLY ACTIVE COMPONENTS OF THE ESSENTIAL OIL OF Ligularia macrophylla (Ledeb.) DC.
Abstract
This report presents the results of a study of the biologically active components of the essential oils obtained from the raw material of Ligularia macrophylla (Ledeb.) DC. collected at the flowering stage in the valley of the Zharly River in the vicinity of the village of Nurken, Karkaraly District, Karaganda Region, Republic of Kazakhstan. The component composition of the essential oils isolated from the aerial and underground parts of Ligularia macrophylla (Ledeb.) DC. was studied by gas chromatography–mass spectrometry on an Agilent 7890B/5977B gas chromatograph with a mass-selective detector. The components of the essential oils were identified by comparison of their mass spectra and linear retention indices (relative to C7–C40 alkanes). In the essential oil from the aerial part of Ligularia macrophylla (Ledeb.) DC. obtained by hydrodistillation, 52 components were detected, of which 43 were identified. The main components of the essential oil from the aerial part of Ligularia macrophylla (Ledeb.) DC. are Д3-carene – 35.16% and cis-в-ocimene – 18.27%. In the essential oil from the aerial part of Ligularia macrophylla (Ledeb.) DC. obtained by microwave extraction, 63 components were detected and 55 were identified, the main components among them being Д3-carene – 24.62% and cis-в-ocimene – 15.16%. By gas chromatography–mass spectrometry, 58 components were detected in the essential oil from the roots of Ligularia macrophylla (Ledeb.) DC. obtained by hydrodistillation, of which 51 were identified. The main components of the essential oil from the roots of Ligularia macrophylla (Ledeb.) DC. obtained by hydrodistillation are Д3-carene – 30.68%, в-bisabolene – 16.01% and в-myrcene – 11.94%.
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